Bioinformatics eScience gateway services using the HP-­SEE infrastructure

• Miklos Kozlovszky (OU)
• Gergely Windisch (Obuda University - Hungary)
• Akos Balasko (Research assistant)

Room: L0-­‐223.1 (building L, ground floor) HP-SEE project is developing and integrating supercomputing centers in the SEE region. This presentation describes online bioinformatics services developed for the regional Life Science virtual organization. With gUSE/WS-PGRADE we have created successfully an online Bioinformatics eScience Gateway, which provides a collection of different type of bioinformatics services for the researchers. The Deep Aligner service is capable to serve short fragment sequence alignment demand of the regional bioinformatics communities within the SEE region. The Disease Gene Mapper service can help researchers to do comparative analysis and target candidate genes for further research of polygene type diseases. We have implemented bioinformatics workflow built up by data mining and data alignment methods to do comparative gene analysis and large scale short fragment sequence alignment tasks. The developed services are using external online open-access eukaryotic (human, animal: mouse, rat, B. rerio, etc.) databases. Beside the workflows we have implemented the GUI for the end-users and build up a WS-PGRADE/gUSE based web portal to facilitate the research work and opened it as online HP-SEE Bioinformatics eScience Gateway for the regional research communities.